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Genomic modeling of tumor onset and progression in a mouse model of aggressive human liver cancer

A comprehensive understanding of molecular mechanisms driving cancer onset and progression should provide a basis for improving early diagnosis, biomarker discovery and treatment options. A key value of genetically engineered mice for modeling human cancer is the possibility to analyze the entire pr...

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Détails bibliographiques
Auteurs principaux: Coulouarn, Cédric, Factor, Valentina M., Conner, Elizabeth A., Thorgeirsson, Snorri S.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179421/
https://ncbi.nlm.nih.gov/pubmed/21771728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr133
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