Llwytho...

BAX enhances paclitaxel-induced apoptosis through a p53-independent pathway

To investigate the role of BAX in chemotherapy-induced apoptosis, we transfected the SW626 human ovarian cancer cell line, which lacks functional p53, with a cDNA encoding for murine BAX. Immunoblotting revealed that BAX transfectants expressed a mean of 10-fold increased levels of BAX compared with...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Strobel, Thomas, Swanson, Linda, Korsmeyer, Stanley, Cannistra, Stephen A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences of the USA 1996
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC19500/
https://ncbi.nlm.nih.gov/pubmed/8943066
Tagiau: Ychwanegu Tag
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