BAX enhances paclitaxel-induced apoptosis through a p53-independent pathway
To investigate the role of BAX in chemotherapy-induced apoptosis, we transfected the SW626 human ovarian cancer cell line, which lacks functional p53, with a cDNA encoding for murine BAX. Immunoblotting revealed that BAX transfectants expressed a mean of 10-fold increased levels of BAX compared with...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1996
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19500/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943066/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.24.14094 |
| Oznake: |
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