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p53-dependent and -independent responses to cisplatin in mouse testicular teratocarcinoma cells

Testicular cancers respond favorably to chemotherapy with the platinum-containing drug cis-diamminedichloroplatinum(II) (cisplatin). One factor that could explain the efficacy of cisplatin is the low frequency of p53 mutations observed in this tumor type. The present study examines the p53-mediated...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Zamble, Deborah B., Jacks, Tyler, Lippard, Stephen J.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1998
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27612/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9600935/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.11.6163
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