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p53-dependent and -independent responses to cisplatin in mouse testicular teratocarcinoma cells

Testicular cancers respond favorably to chemotherapy with the platinum-containing drug cis-diamminedichloroplatinum(II) (cisplatin). One factor that could explain the efficacy of cisplatin is the low frequency of p53 mutations observed in this tumor type. The present study examines the p53-mediated...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zamble, Deborah B., Jacks, Tyler, Lippard, Stephen J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC27612/
https://ncbi.nlm.nih.gov/pubmed/9600935
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