Toxicity associated with repeated administration of first-generation adenovirus vectors does not occur with a helper-dependent vector.

BACKGROUND: Certain gene therapy protocols may require multiple administrations of vectors to achieve therapeutic benefit to the patient. This may be especially relevant for vectors such as adenoviral vectors that do not integrate into the host chromosome. Because immunocompetent animal models used...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: O'Neal, W. K., Zhou, H., Morral, N., Langston, C., Parks, R. J., Graham, F. L., Kochanek, S., Beaudet, A. L.
Format: Artigo
Langue:Inglês
Publié: 2000
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949942/
https://ncbi.nlm.nih.gov/pubmed/10965494
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires