Toxicity associated with repeated administration of first-generation adenovirus vectors does not occur with a helper-dependent vector.

Lignende værker

• Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons
  af: Morral, Núria, et al.
  Udgivet: (1999)
• Development of a complementing cell line and a system for construction of adenovirus vectors with E1 and E2a deleted.
  af: Zhou, H, et al.
  Udgivet: (1996)
• Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector.
  af: Mitani, K, et al.
  Udgivet: (1995)
• Vector and Helper Genome Rearrangements Occur During Production of Helper-Dependent Adenoviral Vectors
  af: Ahn, Miwon, et al.
  Udgivet: (2013)
• Effects of Stuffer DNA on Transgene Expression from Helper-Dependent Adenovirus Vectors
  af: Parks, Robin J., et al.
  Udgivet: (1999)