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XRab40 and XCullin5 form a ubiquitin ligase complex essential for the noncanonical Wnt pathway

Rab GTPases are key regulators of intracellular membrane trafficking. We sought to elucidate the roles of Rab GTPases in Xenopus gastrulation, and found that a Xenopus homolog of Rab40 (XRab40) is required for normal gastrulation. XRab40 is localized at the Golgi apparatus and interacts with Elongin...

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Detalhes bibliográficos
Main Authors: Lee, Rebecca Hui Kwan, Iioka, Hidekazu, Ohashi, Masato, Iemura, Shun-ichiro, Natsume, Tohru, Kinoshita, Noriyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949004/
https://ncbi.nlm.nih.gov/pubmed/17627283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601781
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