XRab40 and XCullin5 form a ubiquitin ligase complex essential for the noncanonical Wnt pathway

Rab GTPases are key regulators of intracellular membrane trafficking. We sought to elucidate the roles of Rab GTPases in Xenopus gastrulation, and found that a Xenopus homolog of Rab40 (XRab40) is required for normal gastrulation. XRab40 is localized at the Golgi apparatus and interacts with Elongin...

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Détails bibliographiques
Auteurs principaux: Lee, Rebecca Hui Kwan, Iioka, Hidekazu, Ohashi, Masato, Iemura, Shun-ichiro, Natsume, Tohru, Kinoshita, Noriyuki
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2007
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949004/
https://ncbi.nlm.nih.gov/pubmed/17627283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601781
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