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A novel ubiquitin-binding protein ZNF216 functioning in muscle atrophy
The ubiquitin–proteasome system (UPS) is critical for specific degradation of cellular proteins and plays a pivotal role on protein breakdown in muscle atrophy. Here, we show that ZNF216 directly binds polyubiquitin chains through its N-terminal A20-type zinc-finger domain and associates with the 26...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1383529/ https://ncbi.nlm.nih.gov/pubmed/16424905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600945 |
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