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A novel ubiquitin-binding protein ZNF216 functioning in muscle atrophy

The ubiquitin–proteasome system (UPS) is critical for specific degradation of cellular proteins and plays a pivotal role on protein breakdown in muscle atrophy. Here, we show that ZNF216 directly binds polyubiquitin chains through its N-terminal A20-type zinc-finger domain and associates with the 26...

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Detalhes bibliográficos
Main Authors: Hishiya, Akinori, Iemura, Shun-ichiro, Natsume, Tohru, Takayama, Shinichi, Ikeda, Kyoji, Watanabe, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383529/
https://ncbi.nlm.nih.gov/pubmed/16424905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600945
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