PKCδ is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movements

Protein kinase C (PKC) has been implicated in the Wnt signaling pathway; however, its molecular role is poorly understood. We identified novel genes encoding δ-type PKC in the Xenopus EST databases. Loss of PKCδ function revealed that it was essential for convergent extension during gastrulation. We...

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Detaylı Bibliyografya
Asıl Yazarlar: Kinoshita, Noriyuki, Iioka, Hidekazu, Miyakoshi, Akira, Ueno, Naoto
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2003
Konular:
Research Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC196137/
https://ncbi.nlm.nih.gov/pubmed/12842914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1101303
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