PKCδ is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movements

Protein kinase C (PKC) has been implicated in the Wnt signaling pathway; however, its molecular role is poorly understood. We identified novel genes encoding δ-type PKC in the Xenopus EST databases. Loss of PKCδ function revealed that it was essential for convergent extension during gastrulation. We...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Kinoshita, Noriyuki, Iioka, Hidekazu, Miyakoshi, Akira, Ueno, Naoto
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2003
Assuntos:	Research Papers
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196137/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12842914/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1101303
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