PKCδ is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movements
Protein kinase C (PKC) has been implicated in the Wnt signaling pathway; however, its molecular role is poorly understood. We identified novel genes encoding δ-type PKC in the Xenopus EST databases. Loss of PKCδ function revealed that it was essential for convergent extension during gastrulation. We...
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| Yayımlandı: | Genes Dev |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cold Spring Harbor Laboratory Press
2003
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196137/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12842914/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1101303 |
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