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PKCδ is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movements

Protein kinase C (PKC) has been implicated in the Wnt signaling pathway; however, its molecular role is poorly understood. We identified novel genes encoding δ-type PKC in the Xenopus EST databases. Loss of PKCδ function revealed that it was essential for convergent extension during gastrulation. We...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Principais autores: Kinoshita, Noriyuki, Iioka, Hidekazu, Miyakoshi, Akira, Ueno, Naoto
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196137/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12842914/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1101303
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