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A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway
Binding of microRNA (miRNA) to mRNA within the RNA-induced silencing complex (RISC) leads to either translational inhibition or to destruction of the target mRNA. Both of these functions are executed by Argonaute 2 (Ago2). Using hematopoiesis in mice as a model system to study the physiological func...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1948855/ https://ncbi.nlm.nih.gov/pubmed/17626790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1565607 |
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