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Function of Piwi, a nuclear Piwi/Argonaute protein, is independent of its slicer activity
The Piwi protein subfamily is essential for Piwi-interacting RNA (piRNA) biogenesis, transposon silencing, and germ-line development, all of which have been proposed to require Piwi endonuclease activity, as validated for two cytoplasmic Piwi proteins in mice. However, recent evidence has led to que...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3557079/ https://ncbi.nlm.nih.gov/pubmed/23297219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213283110 |
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