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Functional replacement of Trypanosoma brucei Argonaute by the human slicer Argonaute2
RNA interference (RNAi) is widespread throughout the eukaryotic lineage, from protozoa to man. Central to all RNAi phenomena is a member of the Argonaute protein family, and, in the case of dsRNA-triggered mRNA cleavage, the Ago protein functions as the RNAi endonuclease or slicer. However, at prese...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1464859/ https://ncbi.nlm.nih.gov/pubmed/16611939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.20806 |
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