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Depletion of newly synthesized Argonaute1 impairs the RNAi response in Trypanosoma brucei
In Trypanosoma brucei, Argonaute1 (TbAGO1) is an essential component of the RNA interference (RNAi) pathway. While characterizing a TbAGO1 conditional knockout cell line, we discovered that, upon blockage of TbAGO1 transcription, the RNAi response to transfected double-stranded RNA was severely inhi...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1894921/ https://ncbi.nlm.nih.gov/pubmed/17526643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.474707 |
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