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Comparative Genomics Reveals Two Novel RNAi Factors in Trypanosoma brucei and Provides Insight into the Core Machinery

The introduction ten years ago of RNA interference (RNAi) as a tool for molecular exploration in Trypanosoma brucei has led to a surge in our understanding of the pathogenesis and biology of this human parasite. In particular, a genome-wide RNAi screen has recently been combined with next-generation...

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Main Authors: Barnes, Rebecca L., Shi, Huafang, Kolev, Nikolay G., Tschudi, Christian, Ullu, Elisabetta
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359990/
https://ncbi.nlm.nih.gov/pubmed/22654659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002678
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