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Essential role of sphingosine 1–phosphate receptor 2 in pathological angiogenesis of the mouse retina
Sphingosine 1–phosphate (S1P), a multifunctional lipid mediator that signals via the S1P family of G protein–coupled receptors (S1PR), regulates vascular maturation, permeability, and angiogenesis. In this study, we explored the role of S1P 2 receptor (S1P(2)R) in normal vascularization and hypoxia-...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1940238/ https://ncbi.nlm.nih.gov/pubmed/17710232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31123 |
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