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Essential role of sphingosine 1–phosphate receptor 2 in pathological angiogenesis of the mouse retina

Sphingosine 1–phosphate (S1P), a multifunctional lipid mediator that signals via the S1P family of G protein–coupled receptors (S1PR), regulates vascular maturation, permeability, and angiogenesis. In this study, we explored the role of S1P 2 receptor (S1P(2)R) in normal vascularization and hypoxia-...

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Bibliografiske detaljer
Main Authors: Skoura, Athanasia, Sanchez, Teresa, Claffey, Kevin, Mandala, Suzanne M., Proia, Richard L., Hla, Timothy
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1940238/
https://ncbi.nlm.nih.gov/pubmed/17710232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31123
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