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Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy
Membrane sphingolipids are metabolized to sphingosine-1-phosphate (S1P), a bioactive lipid mediator that regulates many processes in vertebrate development, physiology, and pathology. Once exported out of cells by cell-specific transporters, chaperone-bound S1P is spatially compartmentalized in the...
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Publicado no: | J Clin Invest |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4409021/ https://ncbi.nlm.nih.gov/pubmed/25831442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76369 |
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