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Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy

Membrane sphingolipids are metabolized to sphingosine-1-phosphate (S1P), a bioactive lipid mediator that regulates many processes in vertebrate development, physiology, and pathology. Once exported out of cells by cell-specific transporters, chaperone-bound S1P is spatially compartmentalized in the...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Proia, Richard L., Hla, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409021/
https://ncbi.nlm.nih.gov/pubmed/25831442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76369
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