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Sphingosine 1-phosphate: lipid signaling in pathology and therapy

Sphingosine 1-phosphate (S1P), a metabolic product of cell membrane sphingolipids, is bound to extracellular chaperones, enriched in circulatory fluids and binds to G protein-coupled S1P receptors (S1PRs) to regulate embryonic development, postnatal organ function and disease. Indeed, S1PRs regulate...

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Bibliografiske detaljer
Udgivet i:Science
Main Authors: Cartier, Andreane, Hla, Timothy
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7661103/
https://ncbi.nlm.nih.gov/pubmed/31624181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar5551
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