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Sphingosine 1-phosphate: lipid signaling in pathology and therapy
Sphingosine 1-phosphate (S1P), a metabolic product of cell membrane sphingolipids, is bound to extracellular chaperones, enriched in circulatory fluids and binds to G protein-coupled S1P receptors (S1PRs) to regulate embryonic development, postnatal organ function and disease. Indeed, S1PRs regulate...
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| Udgivet i: | Science |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7661103/ https://ncbi.nlm.nih.gov/pubmed/31624181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar5551 |
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