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Identification of a chloride ion binding site in Na(+)/Cl(−)-dependent transporters

The recent determination of the crystal structure of the leucine transporter from Aquifex aeolicus (aaLeuT) has provided significant insights into the function of neurotransmitter:sodium symporters. Transport by aaLeuT is Cl(−) independent, whereas many neurotransmitter:sodium symporters from higher...

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Détails bibliographiques
Auteurs principaux: Forrest, Lucy R., Tavoulari, Sotiria, Zhang, Yuan-Wei, Rudnick, Gary, Honig, Barry
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1937540/
https://ncbi.nlm.nih.gov/pubmed/17652169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705600104
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