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The Rocking Bundle: A Mechanism for Ion-Coupled Solute Flux by Symmetrical Transporters

Crystal structures of the bacterial amino acid transporter LeuT have provided the basis for understanding the conformational changes associated with substrate translocation by a multitude of transport proteins with the same fold. Biochemical and modeling studies led to a “rocking bundle” mechanism f...

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Bibliografske podrobnosti
Main Authors: Forrest, Lucy R., Rudnick, Gary
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012352/
https://ncbi.nlm.nih.gov/pubmed/19996368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiol.00030.2009
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