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Chloride-dependent conformational changes in the GlyT1 glycine transporter
The human GlyT1 glycine transporter requires chloride for its function. However, the mechanism by which Cl(−) exerts its influence is unknown. To examine the role that Cl(−) plays in the transport cycle, we measured the effect of Cl(−) on both glycine binding and conformational changes. The ability...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7958241/ https://ncbi.nlm.nih.gov/pubmed/33658361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017431118 |
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