Modification of a Putative Third Sodium Site in the Glycine Transporter GlyT2 Influences the Chloride Dependence of Substrate Transport

Neurotransmitter removal from glycine-mediated synapses relies on two sodium-driven high-affinity plasma membrane GlyTs that control neurotransmitter availability. Mostly glial GlyT1 is the main regulator of glycine synaptic levels, whereas neuronal GlyT2 promotes the recycling of synaptic glycine a...

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Publicat a:Front Mol Neurosci
Autors principals: Benito-Muñoz, Cristina, Perona, Almudena, Abia, David, dos Santos, Helena G., Núñez, Enrique, Aragón, Carmen, López-Corcuera, Beatriz
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166138/
https://ncbi.nlm.nih.gov/pubmed/30319354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00347
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