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Single-molecule FRET reveals sugar-induced conformational dynamics in LacY
The N- and C-terminal six-helix bundles of lactose permease (LacY) form a large internal cavity open on the cytoplasmic side and closed on the periplasmic side with a single sugar-binding site at the apex of the cavity near the middle of the molecule. During sugar/H(+) symport, an outward-facing cav...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1937519/ https://ncbi.nlm.nih.gov/pubmed/17502603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700969104 |
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