Nucleocytoplasmic Shuttling of p53 Is Essential for MDM2-Mediated Cytoplasmic Degradation but Not Ubiquitination

As a shuttling protein, p53 is constantly transported through the nuclear pore complex. p53 nucleocytoplasmic transport is carried out by a bipartite nuclear localization signal (NLS) located at its C-terminal domain and two nuclear export signals (NES) located in its N- and C-terminal regions, resp...

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Bibliografische gegevens

Gepubliceerd in:	Mol Cell Biol
Hoofdauteurs:	O'Keefe, Kevin, Li, Huiping, Zhang, Yanping
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Taylor & Francis 2003
Onderwerpen:	Cell Growth and Development
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC193719/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12944468/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.18.6396-6405.2003
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