Nucleocytoplasmic Shuttling of p53 Is Essential for MDM2-Mediated Cytoplasmic Degradation but Not Ubiquitination
As a shuttling protein, p53 is constantly transported through the nuclear pore complex. p53 nucleocytoplasmic transport is carried out by a bipartite nuclear localization signal (NLS) located at its C-terminal domain and two nuclear export signals (NES) located in its N- and C-terminal regions, resp...
محفوظ في:
| الحاوية / القاعدة: | Mol Cell Biol |
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| المؤلفون الرئيسيون: | , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Taylor & Francis
2003
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC193719/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12944468/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.18.6396-6405.2003 |
| الوسوم: |
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