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Biosynthesis of 15-deoxy-Δ(12,14)-PGJ(2) and the ligation of PPARγ
15-deoxy-Δ(12,14)-PGJ(2) (15d-PGJ(2)) has been identified as an endogenous ligand for PPARγ, inducing adipogenesis in vitro. Additional roles for this molecule in the propagation and resolution of inflammation, ligation of NF-κB, and mediation of apoptosis have been proposed. However, quantitative,...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC193665/ https://ncbi.nlm.nih.gov/pubmed/12975479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318012 |
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