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15-deoxy-Δ(12,14)-PGJ(2): endogenous PPARγ ligand or minor eicosanoid degradation product?
15-Deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)) affects gene transcription by activating PPARγ and by covalent addition to transcription factors and signaling molecules, However, it is not known whether the high concentrations of 15d-PGJ(2) required for these responses are consistent with physiolo...
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2003
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC193674/ https://ncbi.nlm.nih.gov/pubmed/12975467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200319796 |
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