15-deoxy-Δ(12,14)-PGJ(2) enhances platelet production from megakaryocytes

Thrombocytopenia is a critical problem that occurs in many hematologic diseases, as well as after cancer therapy and radiation exposure. Platelet transfusion is the most commonly used therapy but has limitations of alloimmunization, availability, and expense. Thus, the development of safe, small, mo...

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Autori principali: O'Brien, Jamie J., Spinelli, Sherry L., Tober, Joanna, Blumberg, Neil, Francis, Charles W., Taubman, Mark B., Palis, James, Seweryniak, Kathryn E., Gertz, Jacqueline M., Phipps, Richard P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2008
Soggetti:
Hemostasis, Thrombosis, and Vascular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581982/
https://ncbi.nlm.nih.gov/pubmed/18755987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-158535
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