15-deoxy-Δ(12,14)-PGJ(2) enhances platelet production from megakaryocytes

Thrombocytopenia is a critical problem that occurs in many hematologic diseases, as well as after cancer therapy and radiation exposure. Platelet transfusion is the most commonly used therapy but has limitations of alloimmunization, availability, and expense. Thus, the development of safe, small, mo...

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Detalhes bibliográficos
Main Authors: O'Brien, Jamie J., Spinelli, Sherry L., Tober, Joanna, Blumberg, Neil, Francis, Charles W., Taubman, Mark B., Palis, James, Seweryniak, Kathryn E., Gertz, Jacqueline M., Phipps, Richard P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Hemostasis, Thrombosis, and Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581982/
https://ncbi.nlm.nih.gov/pubmed/18755987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-158535
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