15-deoxy-Δ(12,14)-PGJ(2) enhances platelet production from megakaryocytes

Thrombocytopenia is a critical problem that occurs in many hematologic diseases, as well as after cancer therapy and radiation exposure. Platelet transfusion is the most commonly used therapy but has limitations of alloimmunization, availability, and expense. Thus, the development of safe, small, mo...

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Hlavní autoři: O'Brien, Jamie J., Spinelli, Sherry L., Tober, Joanna, Blumberg, Neil, Francis, Charles W., Taubman, Mark B., Palis, James, Seweryniak, Kathryn E., Gertz, Jacqueline M., Phipps, Richard P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2008
Témata:
Hemostasis, Thrombosis, and Vascular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581982/
https://ncbi.nlm.nih.gov/pubmed/18755987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-158535
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