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15-deoxy-Δ(12,14)-PGJ(2) induces synoviocyte apoptosis and suppresses adjuvant-induced arthritis in rats

Peroxisome proliferator–activated receptors (PPARs) are members of the nuclear hormone receptor superfamily and have a dominant regulatory role in adipocyte and monocyte differentiation. PPAR-γ agonists are also negative regulators of macrophage activation and have modulatory effects on tumorigenesi...

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Bibliographic Details
Main Authors: Kawahito, Yutaka, Kondo, Motoharu, Tsubouchi, Yasunori, Hashiramoto, Akira, Bishop-Bailey, David, Inoue, Ken-ichiro, Kohno, Masataka, Yamada, Ryoji, Hla, Timothy, Sano, Hajime
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC314310/
https://ncbi.nlm.nih.gov/pubmed/10903334
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