Rosiglitazone alleviates intrahepatic cholestasis induced by α‐naphthylisothiocyanate in mice: The role of circulating 15‐deoxy‐Δ(12,14)‐PGJ(2) and Nogo

BACKGROUND AND PURPOSE: Intrahepatic cholestasis is mainly caused by dysfunction of bile secretion and has limited effective treatment. Rosiglitazone is a synthetic agonist of PPARγ, whose endogenous agonist is 15‐deoxy‐Δ(12,14)‐PGJ(2) (15d‐PGJ(2)). Reticulon 4B (Nogo‐B) is the detectable Nogo prote...

詳細記述

保存先:
書誌詳細
出版年:Br J Pharmacol
主要な著者: Zhang, Shuang, Yu, Miao, Guo, Fangling, Yang, Xiaoxiao, Chen, Yuanli, Ma, Chuanrui, Li, Qi, Wei, Zhuo, Li, Xiaoju, Wang, Hua, Hu, Huaqing, Zhang, Yujue, Kong, Derun, Miao, Qing Robert, Hu, Wenquan, Hajjar, David P., Zhu, Yan, Han, Jihong, Duan, Yajun
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2020
主題:
Research Papers
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042110/
https://ncbi.nlm.nih.gov/pubmed/31658492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14886
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