Alzheimer's disease-affected brain: Presence of oligomeric Aβ ligands (ADDLs) suggests a molecular basis for reversible memory loss

A molecular basis for memory failure in Alzheimer's disease (AD) has been recently hypothesized, in which a significant role is attributed to small, soluble oligomers of amyloid β-peptide (Aβ). Aβ oligomeric ligands (also known as ADDLs) are known to be potent inhibitors of hippocampal long-ter...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gong, Yuesong, Chang, Lei, Viola, Kirsten L., Lacor, Pascale N., Lambert, Mary P, Finch, Caleb E., Krafft, Grant A., Klein, William L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2003
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC193576/
https://ncbi.nlm.nih.gov/pubmed/12925731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1834302100
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