β cell apoptosis in T cell-mediated autoimmune diabetes

Insulin-dependent diabetes mellitus results from T cell-mediated destruction of insulin-producing, pancreatic islet β cells. How this destruction takes place has remained elusive—largely due to the slow kinetics of disease progression. By crossing a transgenic mouse carrying a β cell-specific T cell...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Kurrer, Michael O., Pakala, Syamasundar V., Hanson, Holly L., Katz, Jonathan D.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1997
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19288/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8990188/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.1.213
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