β cell apoptosis in T cell-mediated autoimmune diabetes

Insulin-dependent diabetes mellitus results from T cell-mediated destruction of insulin-producing, pancreatic islet β cells. How this destruction takes place has remained elusive—largely due to the slow kinetics of disease progression. By crossing a transgenic mouse carrying a β cell-specific T cell...

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Bibliographic Details
Main Authors: Kurrer, Michael O., Pakala, Syamasundar V., Hanson, Holly L., Katz, Jonathan D.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences of the USA 1997
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC19288/
https://ncbi.nlm.nih.gov/pubmed/8990188
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