Transgenic expression of the coxsackie/adenovirus receptor enables adenoviral-mediated gene delivery in naïve T cells

The inability to easily and efficiently introduce genes into primary T cells has hampered the investigation of the pathways controlling T cell fate. To enable adenoviral-mediated gene transfer into normal naïve T cells, transgenic (Tg) mice expressing the coxsackie/adenovirus receptor (CAR) in their...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Wan, Yisong Y., Leon, Ronald P., Marks, Reinhard, Cham, Candace M., Schaack, Jerome, Gajewski, Thomas F., DeGregori, James
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17653/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11095726/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.250356297
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