Transgenic expression of the coxsackie/adenovirus receptor enables adenoviral-mediated gene delivery in naïve T cells

The inability to easily and efficiently introduce genes into primary T cells has hampered the investigation of the pathways controlling T cell fate. To enable adenoviral-mediated gene transfer into normal naïve T cells, transgenic (Tg) mice expressing the coxsackie/adenovirus receptor (CAR) in their...

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Bibliographic Details
Main Authors: Wan, Yisong Y., Leon, Ronald P., Marks, Reinhard, Cham, Candace M., Schaack, Jerome, Gajewski, Thomas F., DeGregori, James
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2000
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC17653/
https://ncbi.nlm.nih.gov/pubmed/11095726
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