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Influence of local radiotherapy on penetration of fluconazole into human saliva.

The pharmacokinetics of fluconazole (50 mg, single oral dose) in saliva and plasma were determined for five healthy subjects and five patients who underwent radiotherapy (dose, > 45 Gy over a 6-week period) in the salivary gland area and suffered from oropharyngeal candidiasis. Saliva was collected...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Oliary, J, Tod, M, Louchahi, K, Petitjean, O, Frachet, B, Le Gros, V, Brion, N
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192775/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8109935/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.12.2674
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