Influence of local radiotherapy on penetration of fluconazole into human saliva.

The pharmacokinetics of fluconazole (50 mg, single oral dose) in saliva and plasma were determined for five healthy subjects and five patients who underwent radiotherapy (dose, > 45 Gy over a 6-week period) in the salivary gland area and suffered from oropharyngeal candidiasis. Saliva was collected...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Oliary, J, Tod, M, Louchahi, K, Petitjean, O, Frachet, B, Le Gros, V, Brion, N
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1993
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192775/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8109935/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.12.2674
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