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Influence of local radiotherapy on penetration of fluconazole into human saliva.

The pharmacokinetics of fluconazole (50 mg, single oral dose) in saliva and plasma were determined for five healthy subjects and five patients who underwent radiotherapy (dose, > 45 Gy over a 6-week period) in the salivary gland area and suffered from oropharyngeal candidiasis. Saliva was collected...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Oliary, J, Tod, M, Louchahi, K, Petitjean, O, Frachet, B, Le Gros, V, Brion, N
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 1993
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192775/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8109935/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.12.2674
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