Influence of local radiotherapy on penetration of fluconazole into human saliva.

The pharmacokinetics of fluconazole (50 mg, single oral dose) in saliva and plasma were determined for five healthy subjects and five patients who underwent radiotherapy (dose, > 45 Gy over a 6-week period) in the salivary gland area and suffered from oropharyngeal candidiasis. Saliva was collect...

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Bibliografiske detaljer
Main Authors: Oliary, J, Tod, M, Louchahi, K, Petitjean, O, Frachet, B, Le Gros, V, Brion, N
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC192775/
https://ncbi.nlm.nih.gov/pubmed/8109935
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