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Influence of local radiotherapy on penetration of fluconazole into human saliva.

The pharmacokinetics of fluconazole (50 mg, single oral dose) in saliva and plasma were determined for five healthy subjects and five patients who underwent radiotherapy (dose, > 45 Gy over a 6-week period) in the salivary gland area and suffered from oropharyngeal candidiasis. Saliva was collect...

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Detalhes bibliográficos
Main Authors: Oliary, J, Tod, M, Louchahi, K, Petitjean, O, Frachet, B, Le Gros, V, Brion, N
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC192775/
https://ncbi.nlm.nih.gov/pubmed/8109935
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