Influence of local radiotherapy on penetration of fluconazole into human saliva.

The pharmacokinetics of fluconazole (50 mg, single oral dose) in saliva and plasma were determined for five healthy subjects and five patients who underwent radiotherapy (dose, > 45 Gy over a 6-week period) in the salivary gland area and suffered from oropharyngeal candidiasis. Saliva was collected...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Oliary, J, Tod, M, Louchahi, K, Petitjean, O, Frachet, B, Le Gros, V, Brion, N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192775/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8109935/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.12.2674
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