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Internal structure and visualization of transmembrane domains of the RyR1 calcium release channel by cryo‐EM
RyR1 is an intracellular calcium channel with a central role in muscle contraction. We obtained a three‐dimensional reconstruction of the RyR1 in the closed state at a nominal resolution of ∼10 Å using cryo‐EM. The cytoplasmic assembly consists of a series of interconnected tubular structures that m...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1925259/ https://ncbi.nlm.nih.gov/pubmed/15908964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb938 |
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