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Calcium release channel RyR2 regulates insulin release and glucose homeostasis
The type 2 ryanodine receptor (RyR2) is a Ca(2+) release channel on the endoplasmic reticulum (ER) of several types of cells, including cardiomyocytes and pancreatic β cells. In cardiomyocytes, RyR2-dependent Ca(2+) release is critical for excitation-contraction coupling; however, a functional role...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4463204/ https://ncbi.nlm.nih.gov/pubmed/25844899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79273 |
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