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Internal structure and visualization of transmembrane domains of the RyR1 calcium release channel by cryo‐EM

RyR1 is an intracellular calcium channel with a central role in muscle contraction. We obtained a three‐dimensional reconstruction of the RyR1 in the closed state at a nominal resolution of ∼10 Å using cryo‐EM. The cytoplasmic assembly consists of a series of interconnected tubular structures that m...

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Autors principals: Samsó, Montserrat, Wagenknecht, Terence, Allen, PD
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925259/
https://ncbi.nlm.nih.gov/pubmed/15908964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb938
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