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Is the mammalian serine palmitoyltransferase a high-molecular-mass complex?

SPT (serine palmitoyltransferase) catalyses the rate-limiting step for the de novo synthesis of sphingolipids. Mammalian SPT is believed to be a heterodimer composed of two subunits, SPTLC1 and SPTLC2. We reported previously the identification of a new third SPT subunit, SPTLC3. In the present study...

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Detaylı Bibliyografya
Asıl Yazarlar: Hornemann, Thorsten, Wei, Yu, von Eckardstein, Arnold
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Portland Press Ltd. 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925250/
https://ncbi.nlm.nih.gov/pubmed/17331073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070025
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