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Is the mammalian serine palmitoyltransferase a high-molecular-mass complex?
SPT (serine palmitoyltransferase) catalyses the rate-limiting step for the de novo synthesis of sphingolipids. Mammalian SPT is believed to be a heterodimer composed of two subunits, SPTLC1 and SPTLC2. We reported previously the identification of a new third SPT subunit, SPTLC3. In the present study...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Portland Press Ltd.
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1925250/ https://ncbi.nlm.nih.gov/pubmed/17331073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070025 |
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