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Fast dynamics of supercoiled DNA revealed by single-molecule experiments

The dynamics of supercoiled DNA play an important role in various cellular processes such as transcription and replication that involve DNA supercoiling. We present experiments that enhance our understanding of these dynamics by measuring the intrinsic response of single DNA molecules to sudden chan...

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Bibliographic Details
Main Authors: Crut, Aurélien, Koster, Daniel A., Seidel, Ralf, Wiggins, Chris H., Dekker, Nynke H.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924543/
https://ncbi.nlm.nih.gov/pubmed/17623785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700333104
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